Glucocorticoid Excess
Thu, 12/27/2007 - 00:32 — oxygen
Glucocorticoid Excess
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clinical causes
anesthetic management
treatment
Clinical causes:
-exogenous administration of steroid hormone
-hyperfunction of adrenal cortex ex. adrenocortical adenoma
-ectopic ACTH stimulation syndrome ex. nonpituitary secreting tumor
-Cushings Disease: pituitary secreting tumor
Cushings Syndrome:
-muscle wasting
-weakness
-osteoporosis
-central obesity
-abdominal striae
-glucose intolerance
-hypertension
-altered mental status
Treatment:
-spironolactone (aldosterone anatagonist, K+ sparring)
-potassium supplementation
Anesthetic management:
-hypervolemic patient therefore avoid fluid overload
-hypokalemic patient therefore metabolic alkalosis
clinical causes
anesthetic management
treatment
Clinical causes:
-exogenous administration of steroid hormone
-hyperfunction of adrenal cortex ex. adrenocortical adenoma
-ectopic ACTH stimulation syndrome ex. nonpituitary secreting tumor
-Cushings Disease: pituitary secreting tumor
Cushings Syndrome:
-muscle wasting
-weakness
-osteoporosis
-central obesity
-abdominal striae
-glucose intolerance
-hypertension
-altered mental status
Treatment:
-spironolactone (aldosterone anatagonist, K+ sparring)
-potassium supplementation
Anesthetic management:
-hypervolemic patient therefore avoid fluid overload
-hypokalemic patient therefore metabolic alkalosis
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"When you treat a disease, first treat the mind."
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