Anesthesia

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Pharmacokinetics -Inhalational Anesthetics

Sat, 11/03/2007 - 18:48 — oxygen
Your Ad Here PHARMACOKINECTICS: Listen to Audio -factors affecting inspiratory concentrations (FI) -factors affecting alveolar concentrations (FA) -factors affecting arterial concentrations (Fa) -factors affecting elimination FACTORS AFFECTING INSPIRED CONCENTRATIONS: (FI) Inspired gas mixture generally depends on: -fresh gas flow rate (FGF) -volume of breathing circuit -machine or breathing circuit absorption ex. high FGF lead to a smaller breathing system volume and lower absortion by the circuit therefore the inspired gas concentration will be closer to the fresh gas concentration FACTORS AFFECTING ALVEOLAR CONCENTRATIONS (FA) -uptake of anesthetics -ventilation -concentration effect -second gas effect (concentrating effect, and augmented inflow effect) FACTORS AFFECTING ARTERIAL CONCENTRATIONS (Fa) -ventilation/perfusion mismatching

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