Anesthesia

Contractility

Contractility Listen to Audio cardiobody_2.jpg -intrinsic ability of the heart to pump -related to shortening of the myocardial fiber muscle -dependant on intracellular calcium during systole Contractility is affected by: -neural influence -humoral influence -pharmacological influence Sympathetic nervous system -usually most important effect on cardiac contractility -affects the atrium, ventricle and nodal tissue Factors which may decrease myocardial contractility: -anoxia -hypoxia -catecholamine storage depletion -ischemia -infarction -anesthetic agents -antiarrhythmic agents

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