Contractility
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-intrinsic ability of the heart to pump
-related to shortening of the myocardial fiber muscle
-dependant on intracellular calcium during systole
Contractility is affected by:
-neural influence
-humoral influence
-pharmacological influence
Sympathetic nervous system
-usually most important effect on cardiac contractility
-affects the atrium, ventricle and nodal tissue
Factors which may decrease myocardial contractility:
-anoxia
-hypoxia
-catecholamine storage depletion
-ischemia
-infarction
-anesthetic agents
-antiarrhythmic agents
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The capability or quality of shrinking or contracting; especially : the power of muscle fibers of shortening into a more compact form. Contractility is the intrinsic ability of the heart to contract independent of preload and afterload. Changes in the ability to produce force during contraction result from different degrees of binding between myosin (thick) and actin (thin) filaments. Nexium 40mg | Buy Sildenafil Citrate
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